West Coast will be without ruckman Tom Hickey because of injury, and premiership star Lewis Jetta serves his one-match suspension this weekend.
Veteran Will Schofield returns, Jake Waterman and Jackson Nelson has been named for his first game of the season, also comes in.
Daniel Venables will also miss out due to concussion.
The 2018 premiers will be looking to make amends on Saturday against the Crows after a last term collapse lead to Adelaide’s victory last time the two sides met.
The Eagles will be looking for their fourth straight win and could finish the weekend off in the top 4.
The Crows have dropped Bryce Gibbs with Wayne Millera coming in as his replacement.